First Lady Michelle Obama and self-made media mogul Oprah Winfrey are two amazing women who have each played significant roles in shaping the way women in power are regarded, respected and recognized in America. As Mrs. Obama prepares to spend her final weeks in the White House ahead of the president's official exit from office next month, Oprah sat down to get her collective thoughts on everything from her most trying times as First Lady, to her husband's legacy, to what she really thinks about the incoming president and much more. Here are 15 amazing quotes from their sit down. You can catch the second airing of the interview on Wednesday, December 21 at 9 p.m. ET on OWN.