The hour-long episode will involve the Academy award-nominated actors, as they conduct fresh and straight-forward conversations about the in and outs of their careers with Ian McKellen and Michael Keaton, respectively.
Both Smith and Jackson have films set to release on Christmas day.
Will Smith stars as Dr. Bennet Omalu biographical sports film, Concussion. Jackson stars in the Quentin Tarantino western, The Hateful Eight.
The Actors on Actors season premiere airs on PBS on Sunday, December 27 at 7 p.m.