The star was left off the best supporting actress category this year.
Her role as Gloria Gaines in Lee Daniels: The Butler was overlooked in the supporting actress category.
"Don't be annoyed," Winfrey said of her reaction. "...I really look at that category and look who is nominated in that category: my friend Julia (Roberts) and June (Squibb) whom I didn't know, but Sally Hawkins and Jennifer (Lawrence) and Lupita (Nyong'o.) I think that's fantastic. And so I haven't picked up the acting chops in 15 years. So to be able to be a part of a film that could get that kind of attention, that could earn the kind of audience respect that it has, I've been saying all along, 'I've already won. I already won.'"
Oprah recently presented her co-star in The Butler Forest Whitaker with the Joel Siegel Award at the Critics Choice Awards.